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Article

Sequence divergence of Mus spretus and Mus musculus across a skin cancer susceptibility locus.

BMC genomics - 23 Dec 2008

Mahler Kimberly L, Fleming Jessica L, Dworkin Amy M, Gladman Nicholas, Cho Hee-Yeon, Mao Jian-Hua, Balmain Allan, Toland Amanda Ewart

Abstract excerpt

BACKGROUND: Mus spretus diverged from Mus musculus over one million years ago. These mice are genetically and phenotypically divergent. Despite the value of utilizing M. musculus and M. spretus for quantitative trait locus (QTL) mapping, relatively little genomic information on M. spretus exists, and most of the available sequence and polymorphic data is for one strain of M. spretus, Spret/Ei. In previous work,...

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Source

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Identifiers

PMID: 19105829
DOI: 10.1186/1471-2164-9-626
PMCID: PMC2628916

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Source receipt: pubmed, retrieved 7 Sept 2026.

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