Article
Identification and characterization of microRNAs controlled by the osteoblast-specific transcription factor Osterix.
PloS one - 1 Jan 2013
Chen Qin, Liu Wenbin, Sinha Krishna M, Yasuda Hideyo, de Crombrugghe Benoit
Abstract excerpt
Osterix (Osx) is an osteoblast-specific transcription factor which is essential for bone formation. MicroRNAs (miRNAs) have been previously shown to be involved in osteogenesis. However, it is unclear whether Osx is involved in the regulation of miRNA expression. In this study, we have identified groups of miRNAs that are differentially expressed in calvaria of the E18.5 Osx(-/-) embryos compared to wild type...
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