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Osteoblast-Specific Transcription Factor Osterix Increases Vitamin D Receptor Gene Expression in Osteoblasts

18 Oct 2011

Abstract excerpt

Osterix (Osx) is an osteoblast-specific transcription factor required for osteoblast differentiation from mesenchymal stem cells. In Osx knock-out mice, no bone formation occurs. The vitamin D receptor (VDR) is a member of the nuclear hormone receptor superfamily that regulates target gene transcription to ensure appropriate control of calcium homeostasis and bone development. Here, we provide several lines of...

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PMID: 22028889
DOI: 10.1371/journal.pone.0026504

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Osteoblast-Specific Transcription Factor Osterix Increases Vitamin D Receptor Gene Expression in OsteoblastsPMID 22028889Read ↗

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