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Article

Novel cytochrome P450-2D6 promoter sequence variations in hepatitis C positive and negative subjects.

Annals of hepatology - 1 Jan 2000

Ho Martin T, Kelly Edward J, Bodor Miklos, Bui Tot, Kowdley Kris V, Ho Rodney J Y

Abstract excerpt

INTRODUCTION: CYP2D6 is a liver enzyme that metabolizes more that 25% of drugs and thus may play a pivotal role in drug-drug interactions. The promoter sequences of cytochrome P450 2D6 (CYP2D6) gene could impact metabolic activity. METHODS: We analyzed genetic variations in the promoter sequence of CYP2D6 gene for 71 hepatitis C negative and 15 hepatitis C positive subjects. RESULTS: We found two novel genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21677335
PMCID: PMC3551345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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