Article
Cancer stem cells in breast cancer.
Histology and histopathology - 1 Jul 2013
Dittmer Jürgen, Rody Achim
Abstract excerpt
There is increasing evidence that cancer stem cells (CSCs) play a critical role in breast cancer initiation, progression, metastasis and drug resistance. It is thought that they are either generated from normal mammary stem/progenitor cells or from mammary epithelial cells by epithelial-mesenchymal transition. Breast CSCs are characterized by the activation of stemness-related pathways, such as the Notch and Wnt...
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