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Breast cancer stem cells: are we ready to go from bench to bedside?

4 Dec 2015

Abstract excerpt

Since the discovery of breast cancer stem cells (BCSCs) more than 10 years ago, a body of exciting research has developed. The intrinsic properties of BCSCs, including self-renewal and the ability to give rise to heterogeneous progeny, make BCSCs a likely source of tumour initiation, heterogeneity, progression and metastasis. BCSCs are also inherently resistant to conventional therapies and are therefore thought...

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PMID: 26768034
DOI: 10.1111/his.12868

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