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Article

The Emerging Picture of Human Breast Cancer as a Stem Cell-based Disease.

Stem cell reviews - 1 Jan 2008

Cobaleda César, Cruz Juan Jesús, González-Sarmiento Rogelio, Sánchez-García Isidro, Pérez-Losada Jesús

Abstract excerpt

There are increasing data supporting the existence of a cell hierarchy within the mammary gland. At the top or this hierarchy a small population of cells with self-renewal properties maintains the tissue architecture and remodeling, and they are known as stem cells. Also, recent evidences indicate that breast cancer is originated and maintained by its own cancer stem cells reminding the normal mammary gland. The...

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Identifiers

PMID: 18401767
DOI: 10.1007/s12015-008-9012-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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