Article
A genomewide screen reveals a role of mitochondria in anaerobic uptake of sterols in yeast.
Molecular biology of the cell - 1 Jan 2006
Reiner Sonja, Micolod Delphine, Zellnig Günther, Schneiter Roger
Abstract excerpt
The mechanisms that govern intracellular transport of sterols in eukaryotic cells are not well understood. Saccharomyces cerevisiae is a facultative anaerobic organism that becomes auxotroph for sterols and unsaturated fatty acids in the absence of oxygen. To identify pathways that are required for uptake and transport of sterols, we performed a systematic screen of the yeast deletion mutant collection for genes...
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