Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ion channels in innate and adaptive immunity.

Annual review of immunology - 1 Jan 2015

Feske Stefan, Wulff Heike, Skolnik Edward Y

Abstract excerpt

Ion channels and transporters mediate the transport of charged ions across hydrophobic lipid membranes. In immune cells, divalent cations such as calcium, magnesium, and zinc have important roles as second messengers to regulate intracellular signaling pathways. By contrast, monovalent cations such as sodium and potassium mainly regulate the membrane potential, which indirectly controls the influx of calcium and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hypersensitivity
Share to Adaptive Immunity
Share to Calcium Channels

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cation Transport Proteins

Share to Immunologic Deficiency Syndromes

Share to Immunotherapy

Share to Ion Channels

Share to Mast Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 25861976
DOI: 10.1146/annurev-immunol-032414-112212
PMCID: PMC4822408

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ion channels in innate and adaptive immunity.PMID 25861976Read ↗

Ion Channels and Transporters in Inflammation: Special Focus on TRP Channels and TRPC6Semantic proximity Read ↗

New Insights on the Role of TRP Channels in Calcium Signalling and Immunomodulation: Review of Pathways and Implications for Clinical PracticeSemantic proximity Read ↗

Ion Channels in AsthmaSemantic proximity Read ↗

What is the evidence for the role of TRP channels in inflammatory and immune cells?Semantic proximity Read ↗

The transient receptor potential superfamily of ion channels.Semantic proximity Read ↗

Kv1.3 in the spotlight for treating immune diseasesSemantic proximity Read ↗

Indispensable Role of Ion Channels and Transporters in the Auditory System.Semantic proximity Read ↗

Potassium channels as therapeutic targets for autoimmune disorders.Semantic proximity Read ↗

The transient receptor potential family of ion channels.Semantic proximity Read ↗

Major channels involved in neuropsychiatric disorders and therapeutic perspectivesSemantic proximity Read ↗

Physiological and pathophysiological functions of SOCE in the immune system.Semantic proximity Read ↗

Ion channels--basic science and clinical disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.