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Article

The COBLL1 C allele is associated with lower serum insulin levels and lower insulin resistance in overweight and obese children.

Diabetes/metabolism research and reviews - 1 Jul 2013

Mancina Rosellina Margherita, Burza Maria Antonella, Maglio Cristina, Pirazzi Carlo, Sentinelli Federica, Incani Michela, Montalcini Tiziana, Pujia Arturo, Congiu Tiziana, Loche Sandro, Pilia Sabrina, Wiklund Olov, Borén Jan, Romeo Stefano, Baroni Marco Giorgio

Abstract excerpt

BACKGROUND: Childhood obesity is a growing epidemic worldwide, and it is associated with metabolic complications, such as insulin resistance. Recently, a genetic variation (rs7607980) in the COBLL1 gene has been associated with lower insulin resistance in adults. The aim of the study was to investigate if the association between COBLL1 rs7607980 genetic variant and lower insulin resistance was present early in...

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PMID: 23463496
DOI: 10.1002/dmrr.2408
PMCID: PMC3799017

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