Article
Association of variants in gastric inhibitory polypeptide receptor gene with impaired glucose homeostasis in obese children and adolescents from Berlin.
European journal of endocrinology - 1 Aug 2010
Sauber Jeannine, Grothe Jessica, Behm Maria, Scherag André, Grallert Harald, Illig Thomas, Hinney Anke, Hebebrand Johannes, Wiegand Susanna, Grüters Annette, Krude Heiko, Biebermann Heike
Abstract excerpt
OBJECTIVE: In the past 20 years, obesity has become a major health problem due to associated diseases like type 2 diabetes mellitus. The gastric inhibitory polypeptide receptor (GIPR) modulates body weight and glucose homeostasis and, therefore, represents an interesting candidate gene for obesity and the comorbidity impaired glucose homeostasis. Recently, a GIPR variation was found to be associated with impaired...
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