Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variants in PTPN22 and SMOC2 genes and the risk of thyroid disease in the Jordanian Arab population.

Endocrine - 1 Dec 2013

Alkhateeb Asem, Marzouka Nour Al-Dain, Tashtoush Reema

Abstract excerpt

Autoimmune thyroid diseases (AITDs) (Hashimoto thyroiditis and Graves' disease) are complex polygenic disorders with multiple genes thought to contribute to the risk of disease. The contribution of these genes differs by different populations. The PTPN22 gene is reported to be associated with multiple autoimmune diseases, but results of association are conflicting in different populations. The SMOC2 gene is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arabs
Share to Autoimmune Diseases
Share to Calcium-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Graves Disease

Share to Hashimoto Disease

Share to Jordan

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Share to Vitiligo

Source

Identifiers

PMID: 23463390
DOI: 10.1007/s12020-013-9908-z

Genes

SMOC2
PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variants in PTPN22 and SMOC2 genes and the risk of thyroid disease in the Jordanian Arab population.PMID 23463390Read ↗

The Relationship between PTPN22 R620W Polymorphisms and the Susceptibility to Autoimmune Thyroid Diseases: An Updated Meta-analysis.Semantic proximity Read ↗

The CD40, CTLA-4, thyroglobulin, TSH receptor, and PTPN22 gene quintet and its contribution to thyroid autoimmunity: back to the future.Semantic proximity Read ↗

SMOC2 gene variant and the risk of vitiligo in Jordanian Arabs.Semantic proximity Read ↗

Why is PTPN22 a good candidate susceptibility gene for autoimmune disease?Semantic proximity Read ↗

The R620W polymorphism of the protein tyrosine phosphatase 22 gene in autoimmune thyroid diseases and rheumatoid arthritis in the Tunisian population.Semantic proximity Read ↗

Association of Protein Tyrosine Phosphatase Nonreceptor 22 (PTPN22) C1858T gene polymorphism with susceptibility to autoimmune thyroid diseases: a meta-analysis.Semantic proximity Read ↗

R620W polymorphism of protein tyrosine phosphatase PTPN22 in Egyptian children and adolescents with systemic lupus erythematosus: relation to thyroid autoimmunity.Semantic proximity Read ↗

The role of PTPN22 in the pathogenesis of autoimmune diseases: A comprehensive review.Semantic proximity Read ↗

Genetic Polymorphism of PTPN22 in Autoimmune Diseases: A Comprehensive Review.Semantic proximity Read ↗

Susceptibility influence of a PTPN22 haplotype with thyroid autoimmunity in Koreans.Semantic proximity Read ↗

<i>PTPN22</i>: Its role in SLE and autoimmunitySemantic proximity Read ↗

[Genetics of thyroid autoimmunity - update and clinical relevance].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.