Susceptibility influence of a PTPN22 haplotype with thyroid autoimmunity in Koreans.

doi:10.1002/dmrr.1265

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Article

Susceptibility influence of a PTPN22 haplotype with thyroid autoimmunity in Koreans.

Diabetes/metabolism research and reviews - 1 Nov 2011

Lee Hye-Soon, Kang Jungoo, Yang Seiwon, Kim Dukhee, Park Yongsoo

Abstract excerpt

BACKGROUND: Considerable amount of evidences in the Caucasians have suggested the association of a missense single-nucleotide polymorphism (SNP) in the protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene (rs2476601) with several autoimmune diseases including autoimmune thyroid diseases (AITD) and type 1 diabetes (T1D). As the SNP was reported to be non-polymorphic in Asians, we attempt to explore an...

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Identifiers

PMID: 22069277
DOI: 10.1002/dmrr.1265

Genes

PTPN22

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Susceptibility influence of a PTPN22 haplotype with thyroid autoimmunity in Koreans.PMID 22069277Read ↗

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The protein tyrosine phosphatase non-receptor type 22 C1858T polymorphism is a joint susceptibility locus for immunthyroiditis and autoimmune diabetes.Semantic proximity Read ↗

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