Article
[Genetics of thyroid autoimmunity - update and clinical relevance].
Medizinische Klinik (Munich, Germany : 1983) - 15 Mar 2009
Dultz Georg, Dittmar Manuela, Kahaly George J
Abstract excerpt
The autoimmune thyroid diseases with the main phenotypes Graves' disease and Hashimoto's thyroiditis belong to the most frequently occurring autoimmune diseases. Genetic factors play a major role in their etiology, and in the past a couple of susceptibility genes have been identified. These are immunoregulatory genes like the HLA class II genes, the CTLA-4 gene and the PTPN22 gene and thyroid-specific genes for...
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