Article
Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets.
Diabetologia - 1 May 2013
Dayeh T A, Olsson A H, Volkov P, Almgren P, Rönn T, Ling C
Abstract excerpt
AIMS/HYPOTHESIS: To date, the molecular function of most of the reported type 2 diabetes-associated loci remains unknown. The introduction or removal of cytosine-phosphate-guanine (CpG) dinucleotides, which are possible sites of DNA methylation, has been suggested as a potential mechanism through which single-nucleotide polymorphisms (SNPs) can affect gene function via epigenetics. The aim of this study was to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
