Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Test for interactions between a genetic marker set and environment in generalized linear models.

Biostatistics (Oxford, England) - 1 Sept 2013

Lin Xinyi, Lee Seunggeun, Christiani David C, Lin Xihong

Abstract excerpt

We consider in this paper testing for interactions between a genetic marker set and an environmental variable. A common practice in studying gene-environment (GE) interactions is to analyze one single-nucleotide polymorphism (SNP) at a time. It is of significant interest to analyze SNPs in a biologically defined set simultaneously, e.g. gene or pathway. In this paper, we first show that if the main effects of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computer Simulation
Share to Gene-Environment Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Markers

Share to Linear Models

Share to Lung Neoplasms

Share to Models, Genetic

Share to Polymorphism, Single Nucleotide

Share to Smoking

Source

Open in PubMed Open full text

Identifiers

PMID: 23462021
DOI: 10.1093/biostatistics/kxt006
PMCID: PMC3769996

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Test for interactions between a genetic marker set and environment in generalized linear models.PMID 23462021Read ↗

A combination test for detection of gene-environment interaction in cohort studies.Semantic proximity Read ↗

SBERIA: set-based gene-environment interaction test for rare and common variants in complex diseases.Semantic proximity Read ↗

Testing gene-environment interactions for rare and/or common variants in sequencing association studies.Semantic proximity Read ↗

Testing gene-environment interactions for rare and/or common variants in sequencing association studiesSemantic proximity Read ↗

Test Gene-Environment Interactions for Multiple Traits in Sequencing Association StudiesSemantic proximity Read ↗

A unified method for rare variant analysis of gene-environment interactions.Semantic proximity Read ↗

Update on the State of the Science for Analytical Methods for Gene-Environment Interactions.Semantic proximity Read ↗

A two-stage testing strategy for detecting genes×environment interactions in association studies.Semantic proximity Read ↗

Multi-trait analysis of gene-by-environment interactions in large-scale genetic studies.Semantic proximity Read ↗

Deciphering Genome Environment Wide Interactions Using Exposed Subjects Only.Semantic proximity Read ↗

A Likelihood Ratio Test for Gene-Environment Interaction Based on the Trend Effect of Genotype Under an Additive Risk Model Using the Gene-Environment Independence Assumption.Semantic proximity Read ↗

Gene-environment interactions using a Bayesian whole genome regression modelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.