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Article

Deciphering Genome Environment Wide Interactions Using Exposed Subjects Only.

Genetic epidemiology - 1 Jul 2015

Zhao Lue Ping, Fan Wenhong, Goodman Gary, Radich Jerry, Martin Paul

Abstract excerpt

The recent successes of genome-wide association studies (GWAS) have renewed interest in genome environment wide interaction studies (GEWIS) to discover genetic factors that modulate penetrance of environmental exposures to human diseases. Indeed, gene-environment interactions (G × E), which have not been emphasized in the GWAS era, could be a source contributing to the missing heritability, a major bottleneck...

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Identifiers

PMID: 25694100
DOI: 10.1002/gepi.21890
PMCID: PMC4469559

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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