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Hepatic IFN-Induced Protein with Tetratricopeptide Repeats Regulation of HCV Infection

1 Mar 2019

Abstract excerpt

Interferons (IFNs) suppress viral infection through the induction of >400 interferon-stimulated genes (ISGs). Among ISGs, IFN-induced protein with tetratricopeptide repeats (IFITs) is one of the most potent and well-characterized ISGs. IFIT family consists of 4 cluster genes. It has been suggested that the antiviral action of each IFIT employs distinct mechanisms. In addition, it has been shown that each IFIT...

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PMID: 30844328
DOI: 10.1089/jir.2018.0103

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