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Article

Identifying Candidate Oocyte Reprogramming Factors Using Cross-Species Global Transcriptional Analysis

1 Apr 2013

Abstract excerpt

There is mounting evidence to suggest that the epigenetic reprogramming capacity of the oocyte is superior to that of the current factor-based reprogramming approaches and that some factor-reprogrammed induced pluripotent stem cells (iPSCs) retain a degree of epigenetic memory that can influence differentiation capacity and may be linked to the observed expression of immunogenicity genes in iPSC derivatives. One...

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PMID: 23458164
DOI: 10.1089/cell.2012.0060

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