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Article

Global Transcriptional Analysis of Oocyte-Based and Factor-Based Nuclear Reprogramming in the Nonhuman Primate

1 Dec 2011

Abstract excerpt

The mechanisms of nuclear reprogramming following somatic cell nuclear transfer (SCNT) to enucleated oocytes or factor-based reprogramming are poorly understood. In this study global transcriptional analysis was performed on a number of different rhesus monkey (Macaca mulatta) cell and tissue samples, including rhesus-induced pluripotent stem cells (IPSCs) and rhesus SCNT-derived embryonic stem cells (SCNT-ESCs)....

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PMID: 21919706
DOI: 10.1089/cell.2011.0033

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