Article

The role of transcription factors in somatic cell nuclear reprogramming by eggs and oocytes

2019-01-01

Abstract excerpt

Somatic cell nuclear reprogramming (SCNR) by eggs is a way to forcibly transform the nuclei of terminally differentiated somatic cells to an embryonic state and gain totipotency (Gurdon et al., 1958). Additionally, induced pluripotency is applied to transform identities of somatic cells to induced pluripotent stem cells by overexpression of combinatorial Yamanaka factors (iPS, Takahashi et al., 2006). Although bot...

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Literature Corpus work: 8f06bba8-7075-5688-abaa-1f05801c4976
DOI: 10.17863/cam.35724

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