Article
Association Study of Gene Polymorphisms in GABA, Serotonin, Dopamine, and Alcohol Metabolism Pathways with Alcohol Dependence in Taiwanese Han Men.
Alcoholism, clinical and experimental research - 1 Feb 2016
Wu Lawrence Shih-Hsin, Lee Chau-Shoun, Weng Tzu-Ya, Wang Kathy Hsiao-Tsz, Cheng Andrew Tai-Ann
Abstract excerpt
BACKGROUND: The roles of GABA, serotonin, dopamine, and alcohol metabolism pathways in alcohol dependence (AD) are evident from animal models and human studies. Aims of this study were to investigate associations between genes in the 4 pathways and AD. METHODS: Male subjects from 2 independent samples of Taiwanese Han descent, a family sample of 179 trios and a case-control sample of 262 AD cases and 273 normal...
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