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Article

IL28B gene polymorphism rs12979860, but not rs8099917, contributes to the occurrence of chronic HCV infection in Uruguayan patients.

Virology journal - 2 Mar 2018

Echeverría Natalia, Chiodi Daniela, López Pablo, Sanchez Ciceron Adriana, Angulo Jenniffer, López-Lastra Marcelo, Silvera Paola, Canavesi Adrian, Bianchi Carla, Colistro Valentina, Cristina Juan, Hernandez Nelia, Moreno Pilar

Abstract excerpt

BACKGROUND: Host single-nucleotide polymorphisms (SNPs) near the interleukin 28B (IL28B) locus are associated with sustained virological response to antiviral therapy and with spontaneous Hepatitis C Virus (HCV) clearance. Prevalence of these SNPs varies depending on ethnicity. The impact of IL28B SNPs in HCV-infected patients is currently unknown in Uruguay. Therefore, the aim of this study was to evaluate and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29499724
DOI: 10.1186/s12985-018-0946-2
PMCID: PMC5833045

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IL28B gene polymorphism rs12979860, but not rs8099917, contributes to the occurrence of chronic HCV infection in Uruguayan patients.PMID 29499724Read ↗

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