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Article

NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent.

Drug and alcohol dependence - 1 May 2013

Zuo Lingjun, Wang Kesheng, Zhang Xiang-Yang, Krystal John H, Li Chiang-Shan R, Zhang Fengyu, Zhang Heping, Luo Xingguang

Abstract excerpt

OBJECTIVE: We aimed to identify novel, functional, replicable and genome-wide significant risk regions specific for alcohol dependence using genome-wide association studies (GWASs). METHODS: A discovery sample (1409 European-American cases with alcohol dependence and 1518 European-American controls) and a replication sample (6438 European-Australian family subjects with 1645 alcohol dependent probands) underwent...

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Identifiers

PMID: 23455491
DOI: 10.1016/j.drugalcdep.2013.02.006
PMCID: PMC3628730

Genes

NKAIN1
SERINC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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