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Article

Genome-wide significant association signals in IPO11-HTR1A region specific for alcohol and nicotine codependence.

Alcoholism, clinical and experimental research - 1 May 2013

Zuo Lingjun, Zhang Xiang-Yang, Wang Fei, Li Chiang-Shan R, Lu Lingeng, Ye Liefu, Zhang Heping, Krystal John H, Deng Hong-Wen, Luo Xingguang

Abstract excerpt

BACKGROUND: Alcohol and nicotine codependence can be considered as a more severe subtype of alcohol dependence. A portion of its risk may be attributable to genetic factors. METHODS: We searched for significant risk genomic regions specific for this disorder using a genome-wide association study. A total of 8,847 subjects underwent gene-disease association analysis, including (i) a discovery cohort of 818...

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Identifiers

PMID: 23216389
DOI: 10.1111/acer.12032
PMCID: PMC3610804

Genes

IPO11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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