Article
[Detection of resistance mutations in proviral DNA in HIV-1 infection].
Enfermedades infecciosas y microbiologia clinica - 1 Feb 2013
Delgado Rafael
Abstract excerpt
Analysis of proviral DNA in HIV infection may have useful applications if techniques that are sufficiently sensitive to detect minor variants, such as single genome sequencing (SGS), are used. This technology, which is performed in DNA from whole blood, improves determination of co-receptor tropism and the detection of both circulating and archived resistance mutations (RM) that are undetectable in plasma. Many...
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