Article
Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.
Gene - 26 Jun 2002
Räty Kaj, Kantola Jaana, Hautala Anne, Hakala Juha, Ylihonko Kristiina, Mäntsälä Pekka
Abstract excerpt
We have cloned and sequenced polyketide synthase (PKS) genes from the aclacinomycin producer Streptomyces galilaeus ATCC 31,615. The sequenced 13.5-kb region contained 13 complete genes. Their organization as well as their protein sequences showed high similarity to those of other type II PKS genes. The continuous region included the genes for the minimal PKS, consisting of ketosynthase I (aknB), ketosynthase II...
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