Article
Embryological-origin-dependent differences in homeobox expression in adult aorta: role in regional phenotypic variability and regulation of NF-κB activity.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2013
Trigueros-Motos Laia, González-Granado José M, Cheung Christine, Fernández Patricia, Sánchez-Cabo Fátima, Dopazo Ana, Sinha Sanjay, Andrés Vicente
Abstract excerpt
OBJECTIVE: Different vascular beds show differing susceptibility to the development of atherosclerosis, but the molecular mechanisms underlying these differences are incompletely understood. This study aims to identify factors that contribute to the phenotypic heterogeneity of distinct regions of the adult vasculature. APPROACH AND RESULTS: High-throughput mRNA profiling in adult mice reveals higher expression of...
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