Article

Second Heart Field-derived Cells Contribute to Angiotensin II-mediated Ascending Aortopathies

2020-02-02

Abstract excerpt

<h4>Background</h4> The ascending aorta is a common location for aneurysm and dissection. This aortic region is populated by a mosaic of medial and adventitial cells that are embryonically derived from either the second heart field (SHF) or the cardiac neural crest. SHF-derived cells populate areas that coincide with the spatial specificity of thoracic aortopathies. The purpose of this study was to determine whet...

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Literature Corpus work: c1401757-9136-5f82-a23f-0093476280e2
DOI: 10.1101/2020.02.02.930917

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