Article
ALOX5 is associated with tuberculosis in a subset of the pediatric population of North China.
Genetic testing and molecular biomarkers - 1 Apr 2013
Shen Chen, Wu Xi-Rong, Wang Bin-Bin, Sun Lin, Jiao Wei-Wei, Wang Jing, Feng Wei-Xing, Xiao Jing, Miao Qing, Liu Fang, Yin Qing-Qin, Ma Xu, Shen A-Dong
Abstract excerpt
BACKGROUND: Genetic factors are involved in the etiology of Mycobacterium tuberculosis infection. Recently, ALOX5 has been identified as a candidate gene for tuberculosis (TB) susceptibility. We investigated whether an association between ALOX5 and TB exists in a Chinese pediatric population from northern China. METHODS: We conducted a case-control study comprising 488 individuals aged 2 months to 17 years by...
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