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Article

LncRNA C5orf64 polymorphisms (rs12518552 and rs2950218) decreases pulmonary tuberculosis susceptibility.

Annals of medicine - 1 Dec 2025

Xu Shilin, Hu Baoping, Zhang Dongfeng, Wang Jing, He Xue, He Yongjun, Wang Yuhe

Abstract excerpt

BACKGROUND: Pulmonary tuberculosis (PTB) remains a significant global health issue, with genetic factors playing a crucial role in susceptibility. Long noncoding RNA (lncRNA) C5orf64 has been implicated in immune responses and cancer, but its association with PTB risk has not been fully explored. METHODS: Genomic DNA was extracted from peripheral blood samples of 955 participants (474 PTB cases and 481 controls)....

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Topics

Humans
RNA, Long Noncoding
Female
Male
Tuberculosis, Pulmonary
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Middle Aged

Adult

Polymorphism, Single Nucleotide

Case-Control Studies

Risk Factors

Genotype

Aged

Smoking

Source

Open in PubMed Open full text

Identifiers

PMID: 40580075
DOI: 10.1080/07853890.2025.2523557
PMCID: PMC12207763

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