Article
Sex- and age-dependent association of SLC11A1 polymorphisms with tuberculosis in Chinese: a case control study.
BMC infectious diseases - 19 Mar 2007
Leung Kim Hung, Yip Shea Ping, Wong Wa Sang, Yiu Lap San, Chan Kam Keung, Lai Wai Man, Chow Eudora Y D, Lin Che Kit, Yam Wing Cheong, Chan Kin Sang
Abstract excerpt
BACKGROUND: Host genetic factors are important determinants in tuberculosis (TB). The SLC11A1 (or NRAMP1) gene has been studied extensively for genetic association with TB, but with inconsistent findings. In addition, no study has yet looked into the effect of sex and age on the relationship between SLC11A1 polymorphisms and TB. METHODS: A case-control study was conducted. In total, 278 pulmonary TB patients and...
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