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Article

Vertebrate intersectin1 is repurposed to facilitate cortical midline connectivity and higher order cognition.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 Feb 2013

Sengar Ameet S, Ellegood Jacob, Yiu Adelaide P, Wang Hua, Wang Wei, Juneja Subhash C, Lerch Jason P, Josselyn Sheena A, Henkelman R Mark, Salter Michael W, Egan Sean E

Abstract excerpt

Invertebrate studies have highlighted a role for EH and SH3 domain Intersectin (Itsn) proteins in synaptic vesicle recycling and morphology. Mammals have two Itsn genes (Itsn1 and Itsn2), both of which can undergo alternative splicing to include DBL/PH and C2 domains not present in invertebrate Itsn proteins. To probe for specific and redundant functions of vertebrate Itsn genes, we generated Itsn1, Itsn2, and...

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Identifiers

PMID: 23447614
DOI: 10.1523/JNEUROSCI.4428-12.2013
PMCID: PMC6619305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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