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Article

Bu-Shen-Ning-Xin Decoction ameliorated the osteoporotic phenotype of ovariectomized mice without affecting the serum estrogen concentration or uterus.

Drug design, development and therapy - 1 Jan 2015

Wang Ling, Qiu Xue-Min, Gui Yu-Yan, Xu Ying-Ping, Gober Hans-Jürgen, Li Da-Jin

Abstract excerpt

INTRODUCTION: Bu-Shen-Ning-Xin Decoction (BSNXD), a traditional Chinese medicinal composition, has been used as a remedy for postmenopausal osteoporosis, but its effects on bone metabolism and the uterus have not been reported. PURPOSE: We aimed to determine the respective effects of BSNXD on the bones and the uterus of ovariectomized (OVX) mice to evaluate the efficacy and safety of this herbal formula....

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Identifiers

PMID: 26357466
DOI: 10.2147/DDDT.S89505
PMCID: PMC4560509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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