Article
Genetic analysis of the Trichuris muris-induced model of colitis reveals QTL overlap and a novel gene cluster for establishing colonic inflammation.
BMC genomics - 26 Feb 2013
Levison Scott E, Fisher Paul, Hankinson Jenny, Zeef Leo, Eyre Steve, Ollier William E, McLaughlin John T, Brass Andy, Grencis Richard K, Pennock Joanne L
Abstract excerpt
BACKGROUND: Genetic susceptibility to colonic inflammation is poorly defined at the gene level. Although Genome Wide Association studies (GWAS) have identified loci in the human genome which confer susceptibility to Inflammatory Bowel Disease (Crohn's and Ulcerative Colitis), it is not clear if p...
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