Article
Increased susceptibility to Trichuris muris infection and exacerbation of colitis in Mdr1a-/- mice.
World journal of gastroenterology - 21 Feb 2014
Bhardwaj Ekta K, Else Kathryn J, Rogan Michael T, Warhurst Geoffrey
Abstract excerpt
AIM: To investigate the influence of Trichuris muris (T. muris) infection in a mouse model of genetic susceptibility to inflammatory bowel disease, Mdr1a-/-. METHODS: Mdr1a-/- mice were housed under specific pathogen free conditions to slow the development of colitis and compared to congenic FVB controls. Mice were infected with approximately 200 embryonated ova from T. muris and assessed for worm burden and...
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