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Article

The Collaborative Cross as a resource for modeling human disease: CC011/Unc, a new mouse model for spontaneous colitis.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 2014

Rogala Allison R, Morgan Andrew P, Christensen Alexis M, Gooch Terry J, Bell Timothy A, Miller Darla R, Godfrey Virginia L, de Villena Fernando Pardo-Manuel

Abstract excerpt

Inflammatory bowel disease (IBD) is an immune-mediated condition driven by improper responses to intestinal microflora in the context of environmental and genetic background. GWAS in humans have identified many loci associated with IBD, but animal models are valuable for dissecting the underlying molecular mechanisms, characterizing environmental and genetic contributions and developing treatments. Mouse models...

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Source

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Identifiers

PMID: 24487921
DOI: 10.1007/s00335-013-9499-2
PMCID: PMC3960486

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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