Article
Quantitative trait loci in a bacterially induced model of inflammatory bowel disease.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2011
Hillhouse Andrew E, Myles Matthew H, Taylor Jeremy F, Bryda Elizabeth C, Franklin Craig L
Abstract excerpt
Inflammatory bowel diseases (IBDs) are complex disorders caused by a combination of environmental, microbial, and genetic factors. Genome-wide association studies in humans have successfully identified multiple genes and loci associated with disease susceptibility, but the mechanisms by which these loci interact with each other and/or with environmental factors (i.e., intestinal microbiota) to cause disease are...
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