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Article

Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2013

Yu Jinpu, Du Weijiao, Yan Fang, Wang Yue, Li Hui, Cao Shui, Yu Wenwen, Shen Chun, Liu Juntian, Ren Xiubao

Abstract excerpt

Myeloid-derived suppressor cells (MDSCs) represent heterogeneous immunosuppressive cells in multiple cancer types and display potent immunosuppressive activity on T cells. We have shown the increased expression of IDO in breast cancer. Because IDO plays a pivotal role in immune tolerance via suppressing T cell function, the aim of this study was to investigate the expression of IDO in MDSCs in breast cancer and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23440412
DOI: 10.4049/jimmunol.1201449

Genes

STAT3
STAT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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