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Article

Antiviral resistance and the control of pandemic influenza: the roles of stochasticity, evolution and model details.

Journal of theoretical biology - 7 Jan 2009

Handel Andreas, Longini Ira M, Antia Rustom

Abstract excerpt

Antiviral drugs, most notably the neuraminidase inhibitors, are an important component of control strategies aimed to prevent or limit any future influenza pandemic. The potential large-scale use of antiviral drugs brings with it the danger of drug resistance evolution. A number of recent studies have shown that the emergence of drug-resistant influenza could undermine the usefulness of antiviral drugs for the...

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Identifiers

PMID: 18952105
DOI: 10.1016/j.jtbi.2008.09.021
PMCID: PMC2624577

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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