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Article

Small cell ovarian carcinoma: genomic stability and responsiveness to therapeutics.

Orphanet journal of rare diseases - 21 Feb 2013

Gamwell Lisa F, Gambaro Karen, Merziotis Maria, Crane Colleen, Arcand Suzanna L, Bourada Valerie, Davis Christopher, Squire Jeremy A, Huntsman David G, Tonin Patricia N, Vanderhyden Barbara C

Abstract excerpt

BACKGROUND: The biology of small cell ovarian carcinoma of the hypercalcemic type (SCCOHT), which is a rare and aggressive form of ovarian cancer, is poorly understood. Tumourigenicity, in vitro growth characteristics, genetic and genomic anomalies, and sensitivity to standard and novel chemotherapeutic treatments were investigated in the unique SCCOHT cell line, BIN-67, to provide further insight in the biology...

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Source

Open in PubMed Open full text

Identifiers

PMID: 23433318
DOI: 10.1186/1750-1172-8-33
PMCID: PMC3635907

Genes

BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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