Article
Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT) beyond SMARCA4 Mutations: A Comprehensive Genomic Analysis.
Cells - 19 Jun 2020
Auguste Aurélie, Blanc-Durand Félix, Deloger Marc, Le Formal Audrey, Bareja Rohan, Wilkes David C, Richon Catherine, Brunn Béatrice, Caron Olivier, Devouassoux-Shisheboran Mojgan, Gouy Sébastien, Morice Philippe, Bentivegna Enrica, Sboner Andrea, Elemento Olivier, Rubin Mark A, Pautier Patricia, Genestie Catherine, Cyrta Joanna, Leary Alexandra
Abstract excerpt
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is an aggressive malignancy that occurs in young women, is characterized by recurrent loss-of-function mutations in the SMARCA4 gene, and for which effective treatments options are lacking. The aim of this study was to broaden the knowledge on this rare malignancy by reporting a comprehensive molecular analysis of an independent cohort of SCCOHT...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.