Article
Absence of clinical correlates of diabetic retinopathy in the Ins2Akita retina.
Clinical & experimental ophthalmology - 1 Aug 2013
McLenachan Samuel, Chen Xiangting, McMenamin Paul G, Rakoczy Elizabeth P
Abstract excerpt
BACKGROUND: The Ins2(Akita) mouse has been reported to display retinal pathology degeneration associated with advanced diabetic retinopathy. In the present study, we monitored retinal changes in these mice to establish if this model displays clinical features associated with advanced diabetic retinopathy in human patients. METHODS: Ins2(Akita) mice (n = 55) on a C57Bl/6J background were monitored clinically from...
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