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Article

Retinal Angiogenesis in the Ins2<sup>Akita</sup>Mouse Model of Diabetic Retinopathy

7 Dec 2012

Abstract excerpt

PURPOSE: Diabetic retinopathy (DR) is the leading cause of blindness among working age adults and does not have any curative treatments. Although chemical- and injury-induced models of retinal neovascularization exist, the need for a genetic model that closely simulates the DR pathologic process is great. METHODS: Here we characterize the development of the retinal disease phenotype in a genetic model of type 1...

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PMID: 23221078
DOI: 10.1167/iovs.12-10959

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