Article
DBA/2J mice are susceptible to diabetic nephropathy and diabetic exacerbation of IOP elevation.
PloS one - 1 Jan 2014
Soto Ileana, Howell Gareth R, John Cai W, Kief Joseph L, Libby Richard T, John Simon W M
Abstract excerpt
Some pathological manifestations of diabetes in the eye include retinopathy, cataracts and elevated intraocular pressure (IOP). Loss of retinal ganglion cells (RGCs) in non-proliferative stages of diabetic retinopathy and small increases in IOP in diabetic patients has raised the possibility that diabetes affects the development and progression of ocular hypertension and glaucoma. The Ins2Akita mutation is known...
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