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Article

Mouse models of polycystic kidney disease induced by defects of ciliary proteins.

BMB reports - 1 Feb 2013

Ko Je Yeong, Park Jong Hoon

Abstract excerpt

Polycystic kidney disease (PKD) is a common hereditary disorder which is characterized by fluid-filled cysts in the kidney. Mutation in either PKD1, encoding polycystin-1 (PC1), or PKD2, encoding polycystin-2 (PC2), are causative genes of PKD. Recent studies indicate that renal cilia, known as mechanosensors, detecting flow stimulation through renal tubules, have a critical function in maintaining homeostasis of...

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Identifiers

PMID: 23433108
DOI: 10.5483/bmbrep.2013.46.2.022
PMCID: PMC4133850

Genes

PKD1
PKD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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