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Article

Role of C-terminal membrane-proximal basic residues in cell surface trafficking of HIV coreceptor GPR15 protein.

The Journal of biological chemistry - 29 Mar 2013

Okamoto Yukari, Bernstein Joshua David, Shikano Sojin

Abstract excerpt

Cell surface density of G protein-coupled receptors (GPCRs) is controlled by dynamic molecular interactions that often involve recognition of the distinct sequence signals on the cargo receptors. We reported previously that the RXR-type dibasic motif in the distal C-terminal tail of an HIV coreceptor GPR15 negatively regulates the cell surface expression by mediating the coatomer protein I complex-dependent...

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Identifiers

PMID: 23430259
DOI: 10.1074/jbc.M112.445817
PMCID: PMC3610991

Genes

GPR15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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