Article
Chronobiology of micturition: putative role of the circadian clock.
The Journal of urology - 1 Sept 2013
Negoro Hiromitsu, Kanematsu Akihiro, Yoshimura Koji, Ogawa Osamu
Abstract excerpt
PURPOSE: Mammals urinate less frequently during the sleep period than the awake period. This is modulated by a triad of factors, including decreased arousal in the brain, a decreased urine production rate in the kidneys and increased functional bladder capacity during sleep. The circadian clock is genetic transcription-translation feedback machinery. It exists in most organs and cells, termed the peripheral...
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