Article
Temporal misalignment of renal sodium transport promotes non-dipping blood pressure phenotypes.
PloS one - 1 Jan 2026
Layton Anita T
Abstract excerpt
Non-dipping blood pressure (BP) phenotypes are strongly associated with cardiovascular and renal morbidity, yet the physiological mechanisms governing nocturnal BP dipping remain incompletely understood. Experimental evidence suggests important roles for circadian timing, renal sodium handling, autonomic regulation, and sleep-wake behavior, but their interactions are difficult to isolate experimentally. We...
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