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Article

Dendritic and stromal cells from the spleen of lupic mice present phenotypic and functional abnormalities.

Molecular immunology - 1 Jul 2013

Gleisner Maria Alejandra, Reyes Paz, Alfaro Jennifer, Solanes Paola, Simon Valeska, Crisostomo Natalia, Sauma Daniela, Rosemblatt Mario, Bono Maria Rosa

Abstract excerpt

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the increase in the percentage of autoreactive B and T lymphocytes. Since dendritic cells (DCs) are essential for B cell and T cell function, we hypothesized that changes in DC biology may play a critical role in the pathogenesis of the disease. We analyzed the phenotype and distribution of two main DC subsets, conventional (cDC) and...

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Identifiers

PMID: 23428837
DOI: 10.1016/j.molimm.2013.01.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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